News Ticker

A global reference for human genetic variation

By Nature

By Nature

The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations. Here we report completion of the project, having reconstructed the genomes of 2,504 individuals from 26 populations using a combination of low-coverage whole-genome sequencing, deep exome sequencing, and dense microarray genotyping. We characterized a broad spectrum of genetic variation, in total over 88 million variants (84.7 million single nucleotide polymorphisms (SNPs), 3.6 million short insertions/deletions (indels), and 60,000 structural variants), all phased onto high-quality haplotypes. This resource includes >99% of SNP variants with a frequency of >1% for a variety of ancestries. We describe the distribution of genetic variation across the global sample, and discuss the implications for common disease studies.


Read the full article by clicking the name of the source below.

In the spotlight

For Certain Christians, Lying for Jesus is Justified in the Abortion Wars

Leviticus 19:11 makes clear: "Ye shall not steal, neither deal falsely, neither lie one to another."There's quite a bit of the Bible that conservative Christian activists tend to leave out, but Biblical prohibitions against lying are routinely given short shrift by those intent on seeing God's will done on Earth. We don't have to look far for examples of it -- from Christians arguing that LGBT people are predators to politicians pretending that being gay is a choice, these lies are common.The Washington Post has a good look at another popular outlet for faith-based lying: the abortion debate, and the notoriously deceptive idea of "crisis pregnancy centers." Reporter Petula Dvorak examines the work of one Virginia activist, Pat Lohman, in particular.shutterstock_296153609
[MORE]

Leave a comment